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The endocannabinoid system and the opioid system interact with each other in many different physiological processes. Both play an important role in pain management. Today, many people treat pain with either one, or they also use it together. There is even an overlap in memory and learning, mood, and addiction. The two systems share a neurochemical, neuroanatomical, and pharmacological characteristics. The opioid and endocannabinoid systems play a role in the control and development of addictions.

To create budder, honey-flavored cannabis oil has to be first made, then processed into a glass or shatter before being extracted into budder with the aid of butane or CO2. This is important because a chemical solvent is needed for the extraction of the THC, after which air pressure and heat are then applied to eliminate the leftover solvent, budder is then extracted when the cannabinoids begin crystallization.

The natural occurring cannabinoid, anandamide, is very similar to THC. But when there is a deficiency of anandamide, it causes migraines. In a study to find out of a deficiency or imbalance in the endocannabinoid system was the cause of migraines, they found that a real deficiency of anandamide caused an imbalance that resulted in migraines. During the study, it was discovered that CBD can correct this imbalance.

The term reverse dabbing simply refers to a dabbing process that makes use of a cold rig. In reverse dabbing the cannabis concentrates are first placed in a cold rig after which a heat source is incorporated to heat it up. Unlike other dabbing techniques that involve heating the rig prior to the incorporation of concentrates, 'the cold start method' starts cold then goes on from there. Cannabis lovers that engage in reverse dabbing site a lot of beneficial attributes of the process including its role in preserving the quality of not just the nail but also the concentrate.

The impact cannabis can have on CTE patients has been under study for quite some time and based on current indications the effects of cannabis on CTE patients are highly individualistic. Every human has a unique endocannabinoid system and as such the level of interaction and responses of each person to cannabinoids varies widely.

Some human trials to test if cannabis is effective in the treatment of neuropathic pain have been executed. Very similar to the result of animal studies, it was found that THC suppresses pain successfully. It was also found, just as with the animal models, that when cannabinoids are taken together with opioids like morphine, the effect is stronger. The positive outcome is that patients that relied fully on morphine, could reduce the dosage significantly. Patients under constant neuropathic pain have trouble sleeping as well. Cannabis also helped with that problem. A combination of CBD and THC also reduced muscle spasms. When THC is taken together with CBD in an equal ratio, the psychotropic effects of THC.

The importance of testing the potency of your cannabutter and cannabis edibles cannot be stressed enough. It doesn't just tell you how strong or potent a batch is, on the flip side it also lets you know if it's weak. A lot of factors like soil conditions, how long it was from the time the plant was harvested to the time it was used, harvesting techniques, environmental factors, etc can affect the level of potency of cannabis and unless properly tested you won't know the level of potency of what you're consuming.

There has long been the discussion about “cannabis at the workplace” and how it will impact the bottom-line for companies. Some people believe that by legalizing cannabis you’ll reduce productivity within the workplace – however, evidence suggests that this is not true. In fact, a recent study showed that in states with medical marijuana on the books – there was nearly a 7% decline in workers’ comp claims. When there were claims, the total period were also shorter than states that didn’t have a medical marijuana program on the books.

cannabis has anti-cancer properties that cause abnormal cells to induce apoptosis (cell death), angiogenesis (forming new blood cells from pre-existing ones), and it also inhibits metastasis and cell proliferation. It is proven in studies that cannabinoids can induce controlled cell death in CD4+ and CD8+ T cell populations. Cannabidiol, CBD, does that due to the formation of reactive oxygen species (ROS).