There's a specific kind of credibility that only comes from the inside. When cannabis advocates say the Controlled Substances Act is a broken instrument of policy failure, it gets filed under "predictable." When a former senior DEA official writes the same thing in a peer-reviewed paper published in Science, it lands differently.

If you find this surprising, you haven't been paying close enough attention to what cannabis has always been in this country. It has never been about public health. It has never been about safety. It has been a political lever, pulled by whoever is in power, against whoever they need to target.

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In 2021, Mexico's Supreme Court declared cannabis prohibition unconstitutional, setting the stage for full legalization. Then Congress proceeded to do absolutely nothing with that ruling for years. The legislative process stalled, got punted, stalled again. So what Mexico ended up with is a patchwork legal reality where your rights exist on paper but the infrastructure to exercise them barely exists at all.

The United States Army just quietly removed one of its longest-standing barriers to enlistment. Recruits with a marijuana-related conviction were previously required to undergo a two-year waiting period, seek a special Pentagon waiver, and pass a drug test. Those restrictions have now been dropped for anyone with a single conviction for possessing marijuana or marijuana-related paraphernalia.

The growth medium is typically agar-based — yes, the same substance used in microbiology to grow bacterial cultures — infused with a formulation derived from something called Murashige and Skoog (MS) salts, a nutrient mixture developed in the 1960s that has become the foundation of plant tissue culture worldwide. To this base, you add specific plant hormones: cytokinins to promote shoot proliferation, auxins to promote rooting, and various other compounds depending on what growth stage you are trying to achieve.

So when the Lancet team searched databases for RCTs treating mental disorders with cannabis as the primary treatment, they found a sparse pool — and then concluded the sparse pool means cannabis doesn't work. That conclusion is circular. You can't run a rigorous trial with plant material you can barely access, in the doses people actually use, then fault the plant for the absence of results.