A brand-new study published in the Canadian Journal of Gastroenterology and Hepatology revealed that cannabis use is linked with a decrease in liver cirrhosis among individuals with hepatitis C.
Epidiolex is designed to treat Dravet syndrome and Lennox-Gestaut syndrome, two rare forms of childhood epilepsy. Coincidentally, pure CBD has also been shown to treat these same conditions.
But how much cannabis is a microdose, exactly? Well, there is no wrong or right answer. It will depend largely on the individual, because cannabis affects everyone differently.
Additionally, the cannabinoids in cannabis also affect the pleasure and reward pathways in your brain that affect your feelings of euphoria and anxiety. This is pretty much how alcohol works in the brain too, but unlike cannabis, the human body doesn’t have its own natural receptors for ethanol.
The main advantage of using cannabis suppositories is the high absorption rate both vaginally and rectally. Just like other kinds of suppositories, when inserted into the body, it places them in direct contact with internal cellular walls, allowing fast absorption into the bloodstream.
The researchers found that CBD interacts with the serotonin (5 HT) receptors which are responsible for managing anxiety. Interestingly, they also found that CBD interacts with the vanilloid (TRPV1) receptors, which is what non-addictive pain killers target in the brain.